Hello there,

I synthesized C-Amidoxime like that

C-Ami electrode fabrication. Carbon felt (Alfa Aesar, 99.0%) was cut into 1 cm2

circular shapes as electrode substrates. Polyacrylonitrile (Sigma-Aldrich,

molecular weight∼150,000), activated carbon was suspended into

N,N -dimethylformamide (DMF) solvent at a mass ratio of 1:1:30. The solution

was stirred overnight to form a uniform slurry. The carbon felt substrate was then

dip-coated with the slurry and air-dried on a hotplate (70◦ C). Then the coated

electrode was put into a water bath (25 ml) stabilized at 70◦ C. 80 mg ml−1

hydroxylamine hydrochloride (Sigma-Aldrich, 99%) and 60 mg ml−1 sodium

carbonate were added into the water bath quickly and the reaction was allowed to

proceed for 90 min (ref. 27). After the reaction, the electrode was washed with

deionized water and air-dried in a furnace (80◦ C) for use.

After that my C-Ami captures metal from metal salts.

Can anyone give me the chemica structural pathway how this happens?

And in that what is the role of sodium carbonate?

I'm having a hard time understanding why this is the kinetic product of this reaction. My point of view is that the tertiary carbocation should be more stable than the secondary (lower activation energy), which would result in the product with the DB on the left side being the kinetic product. I am apperently wrong. Can someone explain to me where my error lies?

The amine group is called "N-Ethylbenzylamine", while the ether group is called "Ethoxymethylbenzene". Why can't the ether group be called "Ethoxybenzyl"?

I get so confused to the naming of benzene, how it turns to phenyl or benzyl, and how I should apply it when naming organic compounds.

EDIT: Is there a general rule on how aromatic hydrocarbons nomenclature differ from each functional groups?

I put B since the first one looked correct but the second one was pointing from a sigma bond which my professor told us cannot be broken to create resonance structures. Thank you for the help

Edit: The correct answer is D. The first one is wrong because the arrow should go to the bond between the carbon and nitrogen rather than to the carbon. As you cannot move lone pairs from one atom to another for resonance. So the arrow should be pointing to the half way point of the bond between the carbon and nitrogen which would move the lone pair off the nitrogen and create a pi bond between those two atoms. The second structure is wrong as you cannot break a sigma bond in resonance.

I'm unsure about the electron pushing on the last step in part B. Would that make an alcohol waste product? Also unsure if deprotonation by TFA is valid in part C.

I want to conjugate a species of carboxylic acid to a Histidine amino acid, and I will protect the NH2 group to hopefully get the Imidazole Nitrogens to attack. Is this feasible?

I already use his free video and find them helpful. I noticed there are much longer versions of some topic available through his channel membership.

For people who have actually watched the longer versions: do they provide substantially more useful explanations and practice than the free video, or is the difference mostly extra examples?

I'm trying to decide whether the membership is worth paying for specifically for physics. (maybe I'll use it in the future for ap chemistry too)

Hi,

I tend to ask long questions so this time I will try to be brief.

Here's a H-NMR spectrum took in 100% DMSO-d6. This is an unknown compound and I try to figure out its overall structure.

Given that the coupling constant of the peak 1 and 2 is really small (2.9 Hz) my hypothesis is that I am looking at a trisubstituted aromatic ring that allows a meta coupling.

I first thought that peak 2 was in fact 2 distinct signals, 2 doublets, but integration rules the thing out.That plus the fact it features exactly the same 2.9 Hz meta coupling than the peak 1.

So my conclusion is :

- peak 1 would be normally a singlet, but is linked by meta coupling to peak 2 so at the end we get a doublet

- peak 2 is a doublet of doublets with a weird and strong second order "roof effect" that give the doublet to the right more intensity

- peak 3 is ortho coupling with peak 2 and should be a plain doublet, but experiences and a even more intense "roof effect"

The look of peak 3 baffles me. Especially the little peak encircled to the right. Maybe it comes from another compound. And the intensity of the "roof effect" makes me doubt.

Anyway, do you the trisubstituted aromatic ring with meta coupling makes sense?

What do you think about peak 3?

If I play with solvents maybe I would be able to spread apart peak 3 and peak 2 and get rid of proximity interference?

Thanks!

I bought the kit because everyone recommended it. But once I got my hands of it, the roughness of the plastics molecules surprised me! It took me 20 minutes and a red pair of hands just to get the old molecule out of a bonding stick. Am I supposed to use the kit more so the plastics soften up? I'm worried about my hands by then. Look forward to hearing your experiences! Thank you.

R prefers to sit pseudoaxial in this half chair due to a steric interaction with R1 when placed pseudoequatorially.

What is this steric interaction called?

I've been calling it 1,2-allylic strain but I guess you could call it 1,3-pseudoallylic strain given the planarity about the N. Are either of these correct? What would you call it?

I'm starting my Master thesis in a month's time on click chemistry.

What would I be doing to get the best out of myself for the lab?

Also, I'd like to know how you'd recommend that I read literature.

What would you do differently or better if you started your master thesis again?

For those of you who regularly use DDQ in organic synthesis, do I really need to purify ddq (and quinones alike) before using them in a reaction?

Thanks!