r/TTC_PCOS • u/Plus-Elderberry-5865 • 1d ago

TTC PCOS

Planning to TTC in 12 months from now.

I have lean PCOS — age 24, optimal BMI, no insulin/androgen issues, but ovulation issues. No other fertility factors.

Specialist recommended trying for a maximum of 6 months given my ovulation issues before starting letrozole + monitored cycles, given the ovulation issues. I am wondering if anyone in my situation has had success with letrozole and if so how many cycles did it take to conceive. Feeling very nervous for the uncertain future and trying to be hopeful.

Also anything recommended to prepare during this year leading up?

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2

u/Upbeat-Hand-2870 39 | PCOS| Currently pregnant | TTC 13months 23h ago

I also have PCOS and wasn’t ovulating on my own. I started taking Metformin and I honestly think that made a huge difference. I did my cycles unmonitored. I tried 2.5mg letrozole and didn’t ovulate. Then I moved up to 5mg and it only took 2 cycles on that dose to conceive! I was taking a lot of supplements and also did Mucinex and pre-seed and added a baby aspirin around 2-3 DPO. I’m 39 so I was pretty surprised it only took 2 cycles on 5mg but everyone is different! If you have any questions I’m happy to try and help

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u/NezzOlive 10h ago

Can you put the list of your supplement please?

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u/Upbeat-Hand-2870 39 | PCOS| Currently pregnant | TTC 13months 9h ago

It’s a lot so I hope I don’t forget anything

Prenatal
B complex
Choline twice a day
Co-Q10 500mg
NAC 600 mg twice a day
Myo-inositol 2g
Melatonin 3mg
Vitamin C 500mg
Vitamin D
Magnesium Glycinate 400mg

My partner was taking a regular men’s multivitamin, vitamin C, vitamin D, and magnesium glycinate

2

u/Similar_Mousse_8389 22h ago

TW MMC

Pcos girly here! I have had success twice ttc baby #2 ! Started letrozole January 2026 and after 4 cycles I got pregnant! However it ended in a MMC at 7.5 weeks on may 29th but it had nothing to do with letrozole. I got my period back on July 24th and I started letrozole again cd 3-7, ovulated on cd 14 and I am now 5 weeks 4 days pregnant—so this one was a first cycle success! Still very early but extremely hopeful! I took 5 mg for all cycles. I was also taking vitamin e, ovasitol, coq10, geritol, drinking pomegranate juice. I also don’t have regular periods/ovulation without the letrozole

1

u/monzzbonzz 16h ago

For me, taking inositol (40:1 ratio) was what helped me get my ovulation back! Ideally you should start taking it 3 months before trying (or earlier)