A teenage girl named Shirley who, with her 'side kick' Bo, (think Sherlock Holmes and Watson) are always in the middle of a new crime that needs solving, and who better to do it than the legendary Sherlock Holmes' great grand-niece Shirley?

Note: some episodes out of order

Archie Goodwin introduces Nero Wolfe as "a man who thinks he's the world's greatest detective. Truth being, he is." Grandly obese and famously eccentric, Wolfe is a genius who lives in—and rarely leaves—a large and comfortably furnished brownstone he owns on West 35th Street in Manhattan. Wolfe maintains an inflexible schedule of reading, tending his 10,000 orchids in the rooftop plant rooms, and dining on the fine cuisine of his master chef, Fritz Brenner. To support his opulent lifestyle and meet the payroll of his live-in staff, Wolfe charges high fees for solving crimes that are beyond the abilities of the police, most often the cigar-chewing Inspector Cramer of Manhattan Homicide. Wolfe sometimes calls upon freelance detectives Saul Panzer, Fred Durkin and Orrie Cather; but he depends upon his assistant Archie Goodwin, the street-smart legman whose wisecracking, irreverent voice narrates the stories.